Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 2475 28
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962 1410 15
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962 951 4
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885 839 55
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923 839 21
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808 627 41
MPO P05164 myeloperoxidase Enzyme 7.1E-15 0.377 0.923 584 17
RBM45 Q8IUH3 RNA binding motif protein 45 2.1E-10 0.383 0.846 557 3
CSF3 P09919 colony stimulating factor 3 0.38 0.377 0.885 552 2
MBL2 P11226 mannose binding lectin 2 Receptor 2.7E-03 0.390 0.846 542 21
HSPA4 P34932 heat shock protein family A (Hsp70) member 4 1.00 0.394 0.923 534 1
GSTP1 P09211 glutathione S-transferase pi 1 1.4E-02 0.383 0.923 520 17
HLA-B P01889 major histocompatibility complex, class I, B 3.9E-05 0.379 0.885 492 40
TBC1D9 Q6ZT07 TBC1 domain family member 9 Enzyme 2.8E-05 0.399 0.846 489 2
DECR1 Q16698 2,4-dienoyl-CoA reductase 1 Enzyme 4.5E-14 0.426 0.885 396 7
PAEP P09466 progestagen associated endometrial protein Enzyme 3.1E-08 0.430 0.846 392 2
ABO P16442 ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase Enzyme 0.427 0.885 384 15
HLA-DQB1 P01920 major histocompatibility complex, class II, DQ beta 1 Immune response 8.9E-03 0.407 0.885 356 10
HLA-DQA1 P01909 major histocompatibility complex, class II, DQ alpha 1 Immune response 2.4E-02 0.416 0.846 346 16
ALDH2 P05091 aldehyde dehydrogenase 2 family member Enzyme 3.4E-10 0.457 0.885 287 18
CYBB P04839 cytochrome b-245 beta chain Ion channel 1.00 0.452 0.885 283 7
FCGR3B O75015 Fc fragment of IgG receptor IIIb Cell adhesion 3.0E-07 0.452 0.962 277 8
NAT2 P11245 N-acetyltransferase 2 Enzyme 3.3E-06 0.451 0.885 273 9
HSPA1B P0DMV8 P0DMV9 heat shock protein family A (Hsp70) member 1B 5.3E-03 0.474 0.808 233 4