Source: BEFREE

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 2475 28
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923 1737 58
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 1533 21
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962 1410 15
IFNG P01579 interferon gamma 0.47 0.288 0.962 1361 10
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962 1334 32
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962 1173 9
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923 1160 28
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885 1156 29
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923 979 70
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962 972 97
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962 926 22
LEP P41159 leptin 0.46 0.349 0.846 807 13
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885 739 21
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885 715 13
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885 706 18
GH1 P01241 growth hormone 1 Signaling 3.0E-02 0.373 0.923 652 15
FOXP3 Q9BZS1 forkhead box P3 0.99 0.368 0.846 622 12
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885 611 20
CXCL10 P02778 C-X-C motif chemokine ligand 10 Signaling 0.37 0.378 0.885 593 8
TIMP1 P01033 TIMP metallopeptidase inhibitor 1 Enzyme modulator 0.50 0.380 0.885 555 4
IL13 P35225 interleukin 13 1.4E-02 0.386 0.846 544 7
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846 518 15
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923 510 6