Source: CURATED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 340 9
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923 285 1
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885 192 93
IFNA2 P01563 interferon alpha 2 0.442 0.885 170 0
CSF3 P09919 colony stimulating factor 3 0.38 0.377 0.885 168 2
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923 164 35
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923 146 14
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962 103 3
ACHE P22303 acetylcholinesterase (Cartwright blood group) Enzyme 1.00 0.445 0.885 100 3
PRL P01236 prolactin Signaling 2.9E-07 0.406 0.885 97 0
ATP7A Q04656 ATPase copper transporting alpha Transporter 1.00 0.494 0.769 90 103
EPO P01588 erythropoietin 1.1E-02 0.381 0.885 90 9
IL2 P60568 interleukin 2 0.48 0.336 0.885 75 3
TYMS P04818 thymidylate synthetase Enzyme 0.72 0.425 0.846 67 4
PARP1 P09874 poly(ADP-ribose) polymerase 1 3.3E-04 0.389 0.923 62 3
HP P00738 haptoglobin Enzyme 1.7E-05 0.412 0.885 62 2
IGF2 P01344 insulin like growth factor 2 4.4E-02 0.390 0.885 59 11
REN P00797 renin Enzyme 2.4E-07 0.370 0.923 53 12
GSR P00390 glutathione-disulfide reductase Enzyme 1.3E-06 0.494 0.846 41 2
CDK6 Q00534 cyclin dependent kinase 6 Kinase 0.98 0.471 0.731 40 23
TNFRSF10A O00220 TNF receptor superfamily member 10a 5.1E-15 0.521 0.731 29 2
PTH P01270 parathyroid hormone 1.2E-02 0.397 0.846 26 3
HAMP P81172 hepcidin antimicrobial peptide 8.2E-03 0.433 0.846 23 9
GATA1 P15976 GATA binding protein 1 0.95 0.483 0.808 22 18