Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 2724 31
IL6 P05231 interleukin 6 0.32 0.248 0.962 2367 22
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923 1899 59
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 1801 22
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 1679 21
IFNG P01579 interferon gamma 0.47 0.288 0.962 1519 11
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962 1483 15
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923 1349 384
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962 1254 10
ALB P02768 albumin Transporter 0.64 0.317 0.962 1198 21
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962 1157 8
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923 1082 82
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962 1049 62
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962 1002 19
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885 933 59
LMNA P02545 lamin A/C 1.00 0.384 0.885 824 285
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962 805 74
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923 783 28
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885 770 23
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962 737 18
CTLA4 P16410 cytotoxic T-lymphocyte associated protein 4 0.94 0.369 0.923 722 24
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885 706 39
IL1RN P18510 interleukin 1 receptor antagonist 3.1E-02 0.373 0.923 701 52
ADIPOQ Q15848 adiponectin, C1Q and collagen domain containing 4.6E-09 0.376 0.885 679 45