Source: BEFREE

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 2475 28
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962 2245 232
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 1604 22
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962 1410 15
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885 1214 67
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962 886 50
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885 839 55
CD34 P28906 CD34 molecule 5.0E-06 0.368 0.808 663 1
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885 611 20
ADIPOQ Q15848 adiponectin, C1Q and collagen domain containing 4.6E-09 0.376 0.885 607 44
CTLA4 P16410 cytotoxic T-lymphocyte associated protein 4 0.94 0.369 0.923 600 18
GSTM1 P09488 glutathione S-transferase mu 1 2.1E-03 0.380 0.923 581 8
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885 563 65
EPO P01588 erythropoietin 1.1E-02 0.381 0.885 560 4
CSF3 P09919 colony stimulating factor 3 0.38 0.377 0.885 552 2
EZH2 Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 1.00 0.376 0.885 535 18
TERT O14746 telomerase reverse transcriptase Enzyme 0.99 0.374 0.846 525 37
NGF P01138 nerve growth factor Signaling 0.82 0.391 0.885 498 6
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846 459 89
CALR P27797 calreticulin Calcium-binding protein 0.89 0.413 0.923 435 5
KLK3 P07288 kallikrein related peptidase 3 Enzyme 4.4E-06 0.443 0.885 350 18
IL5 P05113 interleukin 5 5.7E-03 0.437 0.846 335 1
LOC110806263 TERT 5' regulatory region 0.464 0.731 245 0
ARTN Q5T4W7 artemin Signaling 0.36 0.480 0.846 244 0