Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962 2494 527
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962 1558 50
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923 1193 57
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923 1110 39
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923 1059 13
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885 985 137
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885 824 13
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923 821 17
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885 816 119
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769 816 64
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962 794 14
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923 774 33
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923 747 2600
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808 731 141
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885 706 39
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923 702 98
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962 689 68
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846 679 23
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885 662 37
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846 656 3066
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846 654 55
EPHB2 P29323 EPH receptor B2 Kinase 1.00 0.374 0.846 649 19
FGF2 P09038 fibroblast growth factor 2 Signaling 1.8E-02 0.383 0.923 635 7
GSTM1 P09488 glutathione S-transferase mu 1 2.1E-03 0.380 0.923 627 9