Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923 21
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923 21
LZTR1 Q8N653 leucine zipper like transcription regulator 1 1.0E-92 0.547 0.808 11
RAF1 P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 0.85 0.418 0.885 11
RIT1 Q92963 Ras like without CAAX 1 Enzyme modulator 0.13 0.527 0.808 11
SOS1 Q07889 SOS Ras/Rac guanine nucleotide exchange factor 1 Enzyme modulator 1.00 0.485 0.808 11
ATR Q13535 ATR serine/threonine kinase Kinase 3.5E-09 0.456 0.923 10
CENPJ Q9HC77 centromere protein J Enzyme 2.1E-27 0.546 0.846 10
CEP63 Q96MT8 centrosomal protein 63 Cellular structure 6.2E-25 0.666 0.500 10
ERCC6 P0DP91 Q03468 ERCC excision repair 6, chromatin remodeling factor 5.2E-22 0.507 0.808 1
ERCC8 Q13216 ERCC excision repair 8, CSA ubiquitin ligase complex subunit 2.8E-15 0.551 0.885 1