Source: LHGDN

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 226
IL6 P05231 interleukin 6 0.32 0.248 0.962 177
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962 169
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962 156
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 134
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 112
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962 100
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962 89
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923 88
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962 84
IL18 Q14116 interleukin 18 3.1E-02 0.365 0.923 83
ADIPOQ Q15848 adiponectin, C1Q and collagen domain containing 4.6E-09 0.376 0.885 67
VDR P11473 vitamin D receptor Nuclear receptor 1.7E-05 0.352 0.885 61
CTLA4 P16410 cytotoxic T-lymphocyte associated protein 4 0.94 0.369 0.923 53
CXCL12 P48061 C-X-C motif chemokine ligand 12 0.12 0.379 0.846 53
HLA-DQB1 P01920 major histocompatibility complex, class II, DQ beta 1 Immune response 8.9E-03 0.407 0.885 53
TLR2 O60603 toll like receptor 2 1.0E-06 0.361 0.923 53
CD14 P08571 CD14 molecule 4.9E-05 0.392 0.885 43
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923 39
CXCL10 P02778 C-X-C motif chemokine ligand 10 Signaling 0.37 0.378 0.885 36
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962 34
IL2 P60568 interleukin 2 0.48 0.336 0.885 32
SLC2A1 P11166 solute carrier family 2 member 1 Transporter 0.99 0.388 0.808 31
PTPN22 Q9Y2R2 protein tyrosine phosphatase non-receptor type 22 3.5E-21 0.438 0.846 26