Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
LMNA P02545 lamin A/C 1.00 0.384 0.885 468
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846 342
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846 327
ELN P15502 elastin 2.1E-14 0.415 0.885 257
OFD1 O75665 OFD1 centriole and centriolar satellite protein 0.96 0.510 0.808 225
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808 221
ND1 P03886 NADH dehydrogenase, subunit 1 (complex I) Enzyme 0.522 0.769 214
TRNL1 tRNA 0.534 0.731 213
BAZ1B Q9UIG0 bromodomain adjacent to zinc finger domain 1B 1.00 0.530 0.731 202
POLR3A O14802 RNA polymerase III subunit A Enzyme 1.3E-23 0.538 0.769 198
ND6 P03923 NADH dehydrogenase, subunit 6 (complex I) 0.544 0.808 196
ND5 P03915 NADH dehydrogenase, subunit 5 (complex I) Enzyme 0.531 0.769 195
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885 191
GTF2I P78347 general transcription factor IIi 1.00 0.500 0.808 187
PIEZO2 Q9H5I5 piezo type mechanosensitive ion channel component 2 Ion channel 8.1E-07 0.529 0.769 187
TBL2 Q9Y4P3 transducin beta like 2 1.8E-04 0.538 0.731 185
PTPN22 Q9Y2R2 protein tyrosine phosphatase non-receptor type 22 3.5E-21 0.438 0.846 181
TRNW tRNA 0.563 0.731 181
GTF2IRD1 Q9UHL9 GTF2I repeat domain containing 1 0.90 0.522 0.769 180
ND4 P03905 NADH dehydrogenase, subunit 4 (complex I) Enzyme 0.546 0.769 178
TRNS1 tRNA 0.555 0.808 176
CLIP2 Q9UDT6 CAP-Gly domain containing linker protein 2 Cellular structure 1.00 0.529 0.808 175
LIMK1 P53667 LIM domain kinase 1 Kinase 1.00 0.488 0.731 175
RFC2 P35250 replication factor C subunit 2 Enzyme 2.2E-06 0.520 0.769 175