Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 92
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 90
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923 86
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962 82
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962 76
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923 69
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885 69
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923 64
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923 62
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923 58
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962 54
IL6 P05231 interleukin 6 0.32 0.248 0.962 54
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885 48
FAS P25445 Fas cell surface death receptor 0.81 0.372 0.923 45
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923 45
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885 45
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885 44
NOS1 P29475 nitric oxide synthase 1 1.00 0.408 0.885 44
AGER Q15109 advanced glycosylation end-product specific receptor Receptor 6.4E-16 0.420 0.885 43
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962 41
NQO1 P15559 NAD(P)H quinone dehydrogenase 1 1.2E-09 0.434 0.885 40
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962 40
BECN1 Q14457 beclin 1 Enzyme modulator 0.94 0.432 0.846 39
XDH P47989 xanthine dehydrogenase Enzyme 2.6E-22 0.529 0.846 38