Source: HPO

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
PRKAR1A P10644 protein kinase cAMP-dependent type I regulatory subunit alpha 1.00 0.401 0.846 205
BCOR Q6W2J9 BCL6 corepressor 1.00 0.471 0.808 180
GP1BB P13224 glycoprotein Ib platelet subunit beta 0.51 0.524 0.769 158
TERT O14746 telomerase reverse transcriptase Enzyme 0.99 0.374 0.846 142
AIP O00170 aryl hydrocarbon receptor interacting protein Chaperone 0.36 0.517 0.769 121
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923 119
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885 102
TET2 Q6N021 tet methylcytosine dioxygenase 2 4.3E-54 0.458 0.808 100
TERC telomerase RNA component 0.471 0.846 99
MPL P40238 MPL proto-oncogene, thrombopoietin receptor Receptor 4.1E-09 0.510 0.692 91
TBL1XR1 Q9BZK7 TBL1X receptor 1 1.00 0.534 0.808 91
USP8 P40818 ubiquitin specific peptidase 8 Enzyme 1.00 0.587 0.654 84
SBDS Q9Y3A5 SBDS ribosome maturation factor Enzyme 6.2E-05 0.601 0.692 67
CHST14 Q8NCH0 carbohydrate sulfotransferase 14 Enzyme 0.45 0.638 0.654 59
ZBTB16 Q05516 zinc finger and BTB domain containing 16 Transcription factor 1.00 0.545 0.808 56
CALR P27797 calreticulin Calcium-binding protein 0.89 0.413 0.923 49
PRF1 P14222 perforin 1 5.5E-06 0.540 0.692 48
GP1BA P07359 glycoprotein Ib platelet subunit alpha Receptor 3.2E-03 0.565 0.692 43
STAT5B P51692 signal transducer and activator of transcription 5B Nucleic acid binding 1.00 0.442 0.808 41
IFNG P01579 interferon gamma 0.47 0.288 0.962 40
IRF2BP2 Q7Z5L9 interferon regulatory factor 2 binding protein 2 0.85 0.641 0.500 40
NUMA1 Q14980 nuclear mitotic apparatus protein 1 1.00 0.644 0.577 40
RARA P10276 retinoic acid receptor alpha Nuclear receptor 0.96 0.470 0.846 40
NPM1 P06748 nucleophosmin 1 Chaperone 1.00 0.464 0.846 39