Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808 32 28
SH2B3 Q9UQQ2 SH2B adaptor protein 3 1.0E-04 0.527 0.692 26 8
HFE Q30201 homeostatic iron regulator 2.6E-08 0.436 0.846 22 11
HECTD4 Q9Y4D8 HECT domain E3 ubiquitin protein ligase 4 1.00 0.700 0.462 19 5
PRKAG2 Q9UGJ0 protein kinase AMP-activated non-catalytic subunit gamma 2 Enzyme modulator 1.00 0.582 0.654 14 16
HBS1L Q9Y450 HBS1 like translational GTPase Enzyme 1.9E-07 0.705 0.462 13 104
NAA25 Q14CX7 N-alpha-acetyltransferase 25, NatB auxiliary subunit Enzyme 1.00 0.603 0.692 13 3
CARMIL1 Q5VZK9 capping protein regulator and myosin 1 linker 1 Transcription factor 3.4E-02 0.722 0.500 11 108
TMPRSS6 Q8IU80 transmembrane serine protease 6 Enzyme 4.1E-10 0.584 0.654 11 45
SLC17A1 Q14916 solute carrier family 17 member 1 Transporter 4.1E-16 0.760 0.462 10 160
SLC17A3 O00476 solute carrier family 17 member 3 Transporter 4.9E-22 0.769 0.385 10 59
H2AC6 Q93077 H2A clustered histone 6 Nucleic acid binding 0.60 0.821 0.269 10 18
CHURC1-FNTB P49356 CHURC1-FNTB readthrough 5.3E-05 9 14
H2BC4 P58876 P62807 H2B clustered histone 4 Nucleic acid binding 3.8E-03 0.760 0.269 8 12
MARCHF8 Q5T0T0 membrane associated ring-CH-type finger 8 5.9E-07 0.590 0.692 6 60
MPST P25325 mercaptopyruvate sulfurtransferase Enzyme 3.5E-05 0.588 0.654 6 4
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923 6 2
CMAHP Q9Y471 cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene 0.805 0.346 5 58
SCGN O76038 secretagogin, EF-hand calcium binding protein 2.3E-11 0.695 0.500 5 53
CCND3 P30281 cyclin D3 Enzyme modulator 0.98 0.554 0.654 5 44
PRKCE Q02156 protein kinase C epsilon Kinase 1.00 0.597 0.692 5 32
RCL1 Q9Y2P8 RNA terminal phosphate cyclase like 1 Enzyme 5.9E-02 0.792 0.192 5 28
SLC17A2 O00624 solute carrier family 17 member 2 Transporter 1.4E-06 0.805 0.269 5 22
IKZF1 Q13422 IKAROS family zinc finger 1 Transcription factor 1.00 0.533 0.769 5 19