Source: BEFREE

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 2475 28
IL6 P05231 interleukin 6 0.32 0.248 0.962 2132 21
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923 1737 58
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 1604 22
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962 1410 15
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962 1334 32
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962 1173 9
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885 1156 29
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885 1050 26
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923 1034 19
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962 1011 29
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923 999 26
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962 994 8
LEP P41159 leptin 0.46 0.349 0.846 807 13
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962 762 4
VDR P11473 vitamin D receptor Nuclear receptor 1.7E-05 0.352 0.885 757 66
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923 717 26
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885 715 13
CD44 P16070 CD44 molecule (Indian blood group) 2.4E-07 0.363 0.962 664 32
FOXP3 Q9BZS1 forkhead box P3 0.99 0.368 0.846 622 12
FGF2 P09038 fibroblast growth factor 2 Signaling 1.8E-02 0.383 0.923 546 5
CD14 P08571 CD14 molecule 4.9E-05 0.392 0.885 529 8
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885 514 45
NGF P01138 nerve growth factor Signaling 0.82 0.391 0.885 498 6