Source: INFERRED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923 382
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808 381
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846 342
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923 341
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885 330
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846 327
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846 307
FLNA P21333 filamin A 1.00 0.419 0.846 298
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923 283
CHD7 Q9P2D1 chromodomain helicase DNA binding protein 7 1.00 0.441 0.846 281
PTCH1 Q13635 patched 1 1.00 0.398 0.885 262
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885 229
OFD1 O75665 OFD1 centriole and centriolar satellite protein 0.96 0.510 0.808 225
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962 221
ERCC2 P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 7.1E-20 0.420 0.846 220
GBA P04062 glucosylceramidase beta 1.4E-06 0.500 0.808 220
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846 218
GLI3 P10071 GLI family zinc finger 3 1.00 0.436 0.846 218
PRKAR1A P10644 protein kinase cAMP-dependent type I regulatory subunit alpha 1.00 0.401 0.846 217
MED12 Q93074 mediator complex subunit 12 Transcription factor 1.00 0.476 0.769 216
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808 216
FKRP Q9H9S5 fukutin related protein 9.8E-06 0.513 0.731 209
SUFU Q9UMX1 SUFU negative regulator of hedgehog signaling 1.00 0.493 0.769 209
TBX1 O43435 T-box transcription factor 1 Transcription factor 0.84 0.433 0.808 207