Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846 45
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962 39
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923 33
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923 6
BTK Q06187 Bruton tyrosine kinase Kinase 1.00 0.464 0.808 5
BIRC3 Q13489 baculoviral IAP repeat containing 3 Enzyme modulator 6.6E-02 0.491 0.769 4
U2AF1 P0DN76 Q01081 U2 small nuclear RNA auxiliary factor 1 Nucleic acid binding 0.99 0.604 0.577 3
BCL6 P41182 BCL6 transcription repressor 0.96 0.444 0.808 2
SRSF2 Q01130 serine and arginine rich splicing factor 2 Nucleic acid binding 0.48 0.561 0.731 2
SYK P43405 spleen associated tyrosine kinase Kinase 1.00 0.475 0.808 2
ZRSR2 Q15696 zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2 Nucleic acid binding 1.00 0.751 0.231 2
NFKBIE O00221 NFKB inhibitor epsilon 0.77 0.700 0.385 1
PLCG2 P16885 phospholipase C gamma 2 Enzyme 1.00 0.588 0.808 1
POT1 Q9NUX5 protection of telomeres 1 Nucleic acid binding 0.85 0.560 0.731 1
XPO1 O14980 exportin 1 Receptor 1.00 0.504 0.692 1