Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
IL6 P05231 interleukin 6 0.32 0.248 0.962 2367 22
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962 1028 7
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885 933 59
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808 715 92
CSF3 P09919 colony stimulating factor 3 0.38 0.377 0.885 687 4
CD34 P28906 CD34 molecule 5.0E-06 0.368 0.808 674 3
MPO P05164 myeloperoxidase Enzyme 7.1E-15 0.377 0.923 653 25
KMT2A Q03164 lysine methyltransferase 2A 1.00 0.410 0.885 535 65
TRBV20OR9-2 T cell receptor beta variable 20/OR9-2 (non-functional) 0.403 0.923 456 0
WT1 P19544 WT1 transcription factor Nucleic acid binding 1.00 0.422 0.808 446 61
CDKN2B P42772 cyclin dependent kinase inhibitor 2B 7.3E-03 0.417 0.769 440 13
ABL1 P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 1.00 0.432 0.923 395 37
BCR P11274 BCR activator of RhoGEF and GTPase Enzyme modulator 0.99 0.431 0.885 392 7
KMT2D O14686 lysine methyltransferase 2D 1.00 0.465 0.808 320 266
BMI1 P35226 BMI1 proto-oncogene, polycomb ring finger 0.94 0.448 0.808 309 0
ERG P11308 ETS transcription factor ERG Transcription factor 0.96 0.453 0.808 298 31
ANPEP P15144 alanyl aminopeptidase, membrane Enzyme 3.7E-09 0.462 0.769 280 4
FLT3 P36888 fms related receptor tyrosine kinase 3 Kinase 0.61 0.462 0.654 270 54
IL6ST P40189 interleukin 6 signal transducer Signaling 1.00 0.475 0.808 260 6
SUB1 P53999 SUB1 regulator of transcription 0.89 0.465 0.846 260 3
NM neutrophil migration 0.473 0.808 250 0
YY1 P25490 YY1 transcription factor Transcription factor 0.99 0.481 0.808 245 10
ETV6 P41212 ETS variant transcription factor 6 Transcription factor 0.97 0.477 0.731 241 18
IGFBP7 Q16270 insulin like growth factor binding protein 7 1.3E-03 0.476 0.769 241 8