Source: BEFREE

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 2475 28
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962 2245 232
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923 1737 58
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 1604 22
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 1533 21
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885 1214 67
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923 990 7
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962 951 4
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923 935 11
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962 926 22
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846 888 48
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923 805 39
H3P10 H3 histone pseudogene 10 0.350 0.846 769 0
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923 747 8
IL18 Q14116 interleukin 18 3.1E-02 0.365 0.923 673 18
CD34 P28906 CD34 molecule 5.0E-06 0.368 0.808 663 1
EPHB2 P29323 EPH receptor B2 Kinase 1.00 0.374 0.846 636 9
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808 627 41
CTLA4 P16410 cytotoxic T-lymphocyte associated protein 4 0.94 0.369 0.923 600 18
EPO P01588 erythropoietin 1.1E-02 0.381 0.885 560 4
EZH2 Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 1.00 0.376 0.885 535 18
CD14 P08571 CD14 molecule 4.9E-05 0.392 0.885 529 8
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885 514 45
PARP1 P09874 poly(ADP-ribose) polymerase 1 3.3E-04 0.389 0.923 510 21