Source: INFERRED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
LMNA P02545 lamin A/C 1.00 0.384 0.885 468
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923 341
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923 286
CHD7 Q9P2D1 chromodomain helicase DNA binding protein 7 1.00 0.441 0.846 281
PTCH1 Q13635 patched 1 1.00 0.398 0.885 262
HLA-B P01889 major histocompatibility complex, class I, B 3.9E-05 0.379 0.885 239
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808 221
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962 221
COL1A1 P02452 collagen type I alpha 1 chain 1.00 0.430 0.808 218
SUFU Q9UMX1 SUFU negative regulator of hedgehog signaling 1.00 0.493 0.769 209
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962 191
FLNB O75369 filamin B 6.1E-10 0.458 0.923 187
PTPN22 Q9Y2R2 protein tyrosine phosphatase non-receptor type 22 3.5E-21 0.438 0.846 181
JMJD1C Q15652 jumonji domain containing 1C 1.00 0.517 0.769 169
TPM2 P07951 tropomyosin 2 Cellular structure 2.4E-04 0.530 0.654 162
RREB1 Q92766 ras responsive element binding protein 1 1.00 0.500 0.808 159
CDH23 Q9H251 cadherin related 23 3.2E-06 0.539 0.769 156
RAI1 Q7Z5J4 retinoic acid induced 1 Transcription factor 1.00 0.545 0.731 153
HBB P68871 hemoglobin subunit beta 1.2E-09 0.494 0.808 151
NOTCH2 Q04721 notch receptor 2 1.00 0.441 0.808 149
RERE Q9P2R6 arginine-glutamic acid dipeptide repeats 1.00 0.526 0.846 148
SLC2A1 P11166 solute carrier family 2 member 1 Transporter 0.99 0.388 0.808 148
PIGL Q9Y2B2 phosphatidylinositol glycan anchor biosynthesis class L 6.2E-09 0.581 0.731 146
SETD5 Q9C0A6 SET domain containing 5 1.00 0.560 0.731 145