Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
IL6 P05231 interleukin 6 0.32 0.248 0.962 2367 22
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962 1049 62
TGFA P01135 transforming growth factor alpha Signaling 0.72 0.432 0.885 376 10
CDKN2B-AS1 CDKN2B antisense RNA 1 0.491 0.769 213 183
COL5A1 P20908 collagen type V alpha 1 chain 1.00 0.536 0.769 199 69
WRN Q14191 WRN RecQ like helicase Enzyme 2.6E-34 0.524 0.808 172 89
EYA1 Q99502 EYA transcriptional coactivator and phosphatase 1 0.95 0.531 0.731 168 36
ABCC4 O15439 ATP binding cassette subfamily C member 4 Transporter 1.1E-07 0.536 0.769 146 22
AKR1C3 P42330 aldo-keto reductase family 1 member C3 Enzyme 7.6E-24 0.529 0.769 142 8
GABRB3 P28472 gamma-aminobutyric acid type A receptor subunit beta3 Ion channel 0.95 0.546 0.615 139 56
NRXN1 P58400 Q9ULB1 neurexin 1 1.00 0.581 0.692 139 41
MTHFD1 P11586 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 Enzyme 4.5E-03 0.554 0.769 121 20
TOMM40 O96008 translocase of outer mitochondrial membrane 40 Transporter 0.99 0.590 0.538 113 34
MAD1L1 Q9Y6D9 mitotic arrest deficient 1 like 1 6.8E-16 0.570 0.731 107 45
ECHS1 P30084 enoyl-CoA hydratase, short chain 1 Enzyme 8.8E-04 0.601 0.654 93 26
TLK2 Q86UE8 tousled like kinase 2 Kinase 1.00 0.631 0.538 71 24
FAM13A O94988 family with sequence similarity 13 member A 1.9E-18 0.653 0.462 64 66
MFRP Q9BY79 membrane frizzled-related protein Enzyme 1.3E-15 0.621 0.538 63 22
KALRN O60229 kalirin RhoGEF kinase Kinase 1.00 0.644 0.654 59 28
CADM2 Q8N3J6 cell adhesion molecule 2 0.89 0.670 0.538 58 96
RP1 P56715 RP1 axonemal microtubule associated 4.4E-13 0.663 0.462 57 56
NTHL1 P78549 nth like DNA glycosylase 1 Enzyme 5.7E-10 0.623 0.615 57 11
TRPM3 Q9HCF6 transient receptor potential cation channel subfamily M member 3 Ion channel 5.7E-07 0.663 0.769 51 18
STK24 Q9Y6E0 serine/threonine kinase 24 Kinase 1.1E-02 0.659 0.654 48 12