Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885 20
NOTCH2 Q04721 notch receptor 2 1.00 0.441 0.808 15
CSF3R Q99062 colony stimulating factor 3 receptor Signaling 1.5E-10 0.550 0.692 7
CDK4 P11802 cyclin dependent kinase 4 Kinase 6.3E-02 0.412 0.808 5
EZH2 Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 1.00 0.376 0.885 5
JAK3 P52333 Janus kinase 3 Kinase 5.9E-06 0.505 0.731 5
BLM P54132 BLM RecQ like helicase 1.5E-15 0.535 0.808 4
CDK6 Q00534 cyclin dependent kinase 6 Kinase 0.98 0.471 0.731 3
MYD88 Q99836 MYD88 innate immune signal transduction adaptor Enzyme modulator 0.12 0.414 0.923 3
RHOA P61586 ras homolog family member A Enzyme modulator 0.60 0.502 0.808 3
SOCS1 O15524 suppressor of cytokine signaling 1 Enzyme modulator 0.59 0.445 0.808 3
TNFAIP3 P21580 TNF alpha induced protein 3 Enzyme 1.00 0.481 0.808 3
MAD1L1 Q9Y6D9 mitotic arrest deficient 1 like 1 6.8E-16 0.570 0.731 2
PRF1 P14222 perforin 1 5.5E-06 0.540 0.692 2
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885 1
WAS P42768 WASP actin nucleation promoting factor Cellular structure 1.00 0.529 0.808 1