Source: CURATED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 231 5
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962 179 27
CSF3 P09919 colony stimulating factor 3 0.38 0.377 0.885 168 2
INS P01308 insulin 0.30 0.445 0.923 157 34
ALB P02768 albumin Transporter 0.64 0.317 0.962 123 9
PPARA Q07869 peroxisome proliferator activated receptor alpha Nuclear receptor 3.0E-02 0.432 0.885 67 6
COL4A1 P02462 collagen type IV alpha 1 chain 1.00 0.484 0.731 51 57
MAOA P21397 monoamine oxidase A 1.00 0.465 0.769 48 6
SMAD4 Q13485 SMAD family member 4 Transcription factor 1.00 0.401 0.808 47 136
TTN Q8WZ42 titin Kinase 2.6E-96 0.470 0.885 41 628
HTR7 P34969 5-hydroxytryptamine receptor 7 G-protein coupled receptor 4.5E-02 0.592 0.500 39 0
CRPPA A4D126 CDP-L-ribitol pyrophosphorylase A 2.5E-04 0.566 0.654 21 26
ARG1 P05089 arginase 1 Enzyme 3.6E-04 0.476 0.846 20 39
RNR1 A0A0C5B5G6 s-rRNA 0.626 0.769 20 1
HMGCR P04035 3-hydroxy-3-methylglutaryl-CoA reductase 1.00 0.529 0.692 18 13
CTSB P07858 cathepsin B Enzyme 5.9E-11 0.457 0.846 17 6
HTR3B O95264 5-hydroxytryptamine receptor 3B Ion channel 2.5E-07 0.678 0.423 16 1
EIF2AK4 Q9P2K8 eukaryotic translation initiation factor 2 alpha kinase 4 1.2E-15 0.603 0.577 15 34
CPT2 P23786 carnitine palmitoyltransferase 2 Enzyme 4.6E-10 0.542 0.769 14 73
MICU1 Q9BPX6 mitochondrial calcium uptake 1 Calcium-binding protein 1.9E-13 0.638 0.654 12 5
SLCO1B1 Q9Y6L6 solute carrier organic anion transporter family member 1B1 Transporter 1.1E-21 0.538 0.731 10 19
RAPSN Q13702 receptor associated protein of the synapse 1.5E-03 0.593 0.731 9 21
GFPT1 Q06210 glutamine--fructose-6-phosphate transaminase 1 Enzyme 0.90 0.612 0.654 9 17
AMPD1 P23109 adenosine monophosphate deaminase 1 Enzyme 1.9E-21 0.573 0.692 9 5