Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 2724 31
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 1679 21
IFNG P01579 interferon gamma 0.47 0.288 0.962 1519 11
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923 1337 31
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923 1074 19
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962 1049 62
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962 1028 7
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923 1021 43
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923 1018 185
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962 996 23
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923 992 56
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885 823 34
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962 794 14
FAS P25445 Fas cell surface death receptor 0.81 0.372 0.923 754 47
REN P00797 renin Enzyme 2.4E-07 0.370 0.923 721 25
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846 679 23
HLA-A P04439 major histocompatibility complex, class I, A 1.3E-03 0.370 0.846 672 82
GABPA Q06546 GA binding protein transcription factor subunit alpha Transcription factor 1.00 0.379 0.885 632 0
GSTM1 P09488 glutathione S-transferase mu 1 2.1E-03 0.380 0.923 627 9
LAMC2 Q13753 laminin subunit gamma 2 Enzyme modulator 2.9E-12 0.389 0.923 602 66
RBM45 Q8IUH3 RNA binding motif protein 45 2.1E-10 0.383 0.846 557 3
CD14 P08571 CD14 molecule 4.9E-05 0.392 0.885 551 8
GSTT1 P30711 glutathione S-transferase theta 1 1.5E-04 0.393 0.923 541 0
STAT1 P42224 signal transducer and activator of transcription 1 Nucleic acid binding 1.00 0.399 0.885 531 41