Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 2724 31
IL6 P05231 interleukin 6 0.32 0.248 0.962 2367 22
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 1801 22
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 1679 21
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962 1558 50
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962 1483 15
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923 1337 31
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962 1254 10
ALB P02768 albumin Transporter 0.64 0.317 0.962 1198 21
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962 1174 54
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962 1157 8
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923 1074 19
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923 1059 13
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923 1044 15
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923 1021 43
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962 1002 19
LEP P41159 leptin 0.46 0.349 0.846 931 15
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885 824 13
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769 816 64
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962 805 74
TLR2 O60603 toll like receptor 2 1.0E-06 0.361 0.923 749 15
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962 737 18
ADIPOQ Q15848 adiponectin, C1Q and collagen domain containing 4.6E-09 0.376 0.885 679 45
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885 675 21