Source: CURATED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
INS P01308 insulin 0.30 0.445 0.923 157 34
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885 141 11
LEP P41159 leptin 0.46 0.349 0.846 114 3
GNAS O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 0.68 0.420 0.885 67 40
TFRC P02786 transferrin receptor Enzyme 7.0E-05 0.437 0.885 52 33
CYP19A1 P11511 cytochrome P450 family 19 subfamily A member 1 Enzyme 1.7E-05 0.410 0.885 51 29
BAX Q07812 BCL2 associated X, apoptosis regulator Signaling 0.32 0.417 0.885 51 4
NRG1 Q02297 neuregulin 1 Signaling 1.00 0.464 0.885 50 28
LMNA P02545 lamin A/C 1.00 0.384 0.885 46 247
DMD P11532 dystrophin 1.00 0.423 0.923 41 312
RBP4 P02753 retinol binding protein 4 Transporter 0.52 0.493 0.808 36 9
LHB P01229 luteinizing hormone subunit beta Signaling 2.2E-03 0.638 0.462 29 7
SCNN1A P37088 sodium channel epithelial 1 subunit alpha Ion channel 1.1E-11 0.601 0.577 28 10
RUNX3 Q13761 RUNX family transcription factor 3 Transcription factor 0.84 0.459 0.731 27 11
BCL11A Q9H165 BAF chromatin remodeling complex subunit BCL11A Transcription factor 0.97 0.541 0.769 25 50
AKR1C3 P42330 aldo-keto reductase family 1 member C3 Enzyme 7.6E-24 0.529 0.769 24 3
TOP2A P11388 DNA topoisomerase II alpha 0.99 0.497 0.731 24 2
LIF P15018 LIF interleukin 6 family cytokine Signaling 0.52 0.483 0.769 24 0
GP1BB P13224 glycoprotein Ib platelet subunit beta 0.51 0.524 0.769 23 6
MALAT1 metastasis associated lung adenocarcinoma transcript 1 0.435 0.846 23 0
TBX1 O43435 T-box transcription factor 1 Transcription factor 0.84 0.433 0.808 20 9
AKR1C2 P52895 aldo-keto reductase family 1 member C2 Enzyme 6.9E-11 0.608 0.577 20 5
AKR1C1 Q04828 aldo-keto reductase family 1 member C1 Enzyme 3.5E-15 0.593 0.615 18 1
FOXP3 Q9BZS1 forkhead box P3 0.99 0.368 0.846 16 17