Source: CURATED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923 285 1
IL6 P05231 interleukin 6 0.32 0.248 0.962 270 4
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962 239 0
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962 171 2
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923 167 4
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923 138 40
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885 120 21
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885 115 105
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962 109 7
GSTP1 P09211 glutathione S-transferase pi 1 1.4E-02 0.383 0.923 103 4
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923 96 6
CDH1 P12830 cadherin 1 0.15 0.401 0.808 73 158
TSC2 P49815 TSC complex subunit 2 Enzyme modulator 1.00 0.439 0.808 72 287
MPO P05164 myeloperoxidase Enzyme 7.1E-15 0.377 0.923 60 11
IGF2 P01344 insulin like growth factor 2 4.4E-02 0.390 0.885 59 11
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923 45 8
ABL1 P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 1.00 0.432 0.923 37 28
KRT8 P05787 keratin 8 2.4E-08 0.517 0.654 35 7
ALDH2 P05091 aldehyde dehydrogenase 2 family member Enzyme 3.4E-10 0.457 0.885 34 9
CEBPA P49715 CCAAT enhancer binding protein alpha Transcription factor 0.55 0.496 0.692 33 15
MIR145 microRNA 145 0.431 0.846 32 0
PHB P35232 prohibitin 0.76 0.511 0.846 31 6
STAT5A P42229 signal transducer and activator of transcription 5A Nucleic acid binding 1.00 0.445 0.808 29 0
GJB1 P08034 gap junction protein beta 1 Cell-cell junction 0.85 0.514 0.731 28 85