Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962 2245 232
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923 805 39
ALK Q9UM73 ALK receptor tyrosine kinase Kinase 3.2E-06 0.396 0.846 484 28
CD163 Q86VB7 CD163 molecule Enzyme 8.3E-04 0.427 0.846 341 1
TSHR P16473 thyroid stimulating hormone receptor G-protein coupled receptor 3.0E-15 0.486 0.808 187 52
MOG Q16653 myelin oligodendrocyte glycoprotein Enzyme modulator 0.14 0.546 0.731 116 5
PGD P52209 phosphogluconate dehydrogenase Enzyme 0.99 0.576 0.769 85 1
USP6 P35125 ubiquitin specific peptidase 6 Enzyme 2.9E-35 0.633 0.692 55 0
MARS1 P56192 methionyl-tRNA synthetase 1 2.1E-15 0.638 0.654 37 2
SLA2 Q9H6Q3 Src like adaptor 2 Enzyme modulator 7.6E-02 0.722 0.423 22 0
RHAG Q02094 Rh associated glycoprotein Transporter 1.0E-02 0.716 0.346 20 2