Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 2724 31
IL6 P05231 interleukin 6 0.32 0.248 0.962 2367 22
IFNG P01579 interferon gamma 0.47 0.288 0.962 1519 11
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923 1511 83
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962 1250 33
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885 1206 36
ALB P02768 albumin Transporter 0.64 0.317 0.962 1198 21
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923 1193 57
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885 1119 24
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962 1101 185
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885 1101 12
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885 1083 13
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962 1028 7
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962 1002 19
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923 821 17
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962 737 18
FN1 P02751 fibronectin 1 Signaling 1.4E-03 0.365 0.962 724 33
HMGB1 P09429 high mobility group box 1 Nucleic acid binding 0.82 0.368 0.923 724 10
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846 664 387
IFNA1 P01562 interferon alpha 1 0.371 0.923 662 6
MAPK3 P27361 mitogen-activated protein kinase 3 Kinase 3.7E-02 0.379 0.885 647 7
IFNA13 P01562 interferon alpha 13 0.374 0.923 646 4
CXCL10 P02778 C-X-C motif chemokine ligand 10 Signaling 0.37 0.378 0.885 631 9
STAT1 P42224 signal transducer and activator of transcription 1 Nucleic acid binding 1.00 0.399 0.885 531 41