Source: BEFREE

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923 1737 58
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 1604 22
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 1533 21
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885 1294 19
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962 1173 9
ALB P02768 albumin Transporter 0.64 0.317 0.962 1089 13
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885 1050 26
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962 1011 29
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923 957 6
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962 932 19
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962 926 22
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962 886 50
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923 852 49
LEP P41159 leptin 0.46 0.349 0.846 807 13
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885 765 17
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846 665 33
GH1 P01241 growth hormone 1 Signaling 3.0E-02 0.373 0.923 652 15
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962 638 12
ADIPOQ Q15848 adiponectin, C1Q and collagen domain containing 4.6E-09 0.376 0.885 607 44
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923 572 22
FGF2 P09038 fibroblast growth factor 2 Signaling 1.8E-02 0.383 0.923 546 5
IL13 P35225 interleukin 13 1.4E-02 0.386 0.846 544 7
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962 537 47
HTC2 hypertrichosis 2 (generalized, congenital) 0.392 0.808 511 0