Source: CTD_human

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923 280
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962 234
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962 185
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962 170
CSF3 P09919 colony stimulating factor 3 0.38 0.377 0.885 168
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923 133
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885 111
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962 89
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885 89
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885 87
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923 83
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962 68
NPPA P01160 natriuretic peptide A 5.5E-04 0.505 0.769 61
RELA Q04206 RELA proto-oncogene, NF-kB subunit Transcription factor 1.00 0.406 0.885 59
EPHX1 P07099 epoxide hydrolase 1 3.2E-09 0.500 0.846 57
NOTCH1 P46531 notch receptor 1 1.00 0.369 0.885 56
SMO Q99835 smoothened, frizzled class receptor G-protein coupled receptor 4.3E-07 0.489 0.731 54
CASP8 Q14790 caspase 8 Enzyme 3.7E-06 0.404 0.923 53
GSTT1 P30711 glutathione S-transferase theta 1 1.5E-04 0.393 0.923 48
NOTCH2 Q04721 notch receptor 2 1.00 0.441 0.808 46
IGF1R P08069 insulin like growth factor 1 receptor Kinase 0.97 0.399 0.885 41
FLT1 P17948 fms related receptor tyrosine kinase 1 Kinase 1.00 0.419 0.846 37
PTCH1 Q13635 patched 1 1.00 0.398 0.885 35
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885 34