Source: ANIMAL_MODELS

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 101
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962 94
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923 86
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885 72
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923 64
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923 62
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923 60
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 59
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923 58
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962 55
NOS1 P29475 nitric oxide synthase 1 1.00 0.408 0.885 46
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885 45
AGER Q15109 advanced glycosylation end-product specific receptor Receptor 6.4E-16 0.420 0.885 43
IL18 Q14116 interleukin 18 3.1E-02 0.365 0.923 41
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923 39
CXCL1 P09341 C-X-C motif chemokine ligand 1 Signaling 0.12 0.449 0.923 30
NR3C1 P04150 nuclear receptor subfamily 3 group C member 1 Nuclear receptor 0.97 0.393 0.885 28
MIF P14174 macrophage migration inhibitory factor 1.2E-02 0.412 0.885 26
ANGPT2 O15123 angiopoietin 2 Signaling 0.83 0.410 0.846 25
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923 25
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885 25
MMP3 P08254 matrix metallopeptidase 3 Enzyme 5.7E-15 0.408 0.885 24
NGF P01138 nerve growth factor Signaling 0.82 0.391 0.885 24
S100B P04271 S100 calcium binding protein B Calcium-binding protein 4.4E-02 0.383 0.923 23