Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI g | DPI g | Num. diseases |
---|---|---|---|---|---|---|---|
AIRE | O43918 | autoimmune regulator | 6.7E-12 | 0.550 | 0.621 | 6 | |
CYP19A1 | P11511 | cytochrome P450 family 19 subfamily A member 1 | oxidoreductase | 8.6E-06 | 0.482 | 0.690 | 5 |
FAS | P25445 | Fas cell surface death receptor | 0.84 | 0.393 | 0.862 | 4 | |
IL4 | P05112 | interleukin 4 | 5.3E-03 | 0.364 | 0.931 | 4 | |
MAP3K14 | Q99558 | mitogen-activated protein kinase kinase kinase 14 | 0.648 | 0.552 | 4 | ||
TRAF3IP2 | O43734 | TRAF3 interacting protein 2 | 7.4E-10 | 0.621 | 0.586 | 4 | |
E2F1 | Q01094 | E2F transcription factor 1 | nucleic acid binding; transcription factor | 0.99 | 0.491 | 0.690 | 3 |
IL2 | P60568 | interleukin 2 | 0.49 | 0.373 | 0.931 | 3 | |
IL2RA | P01589 | interleukin 2 receptor subunit alpha | receptor | 5.2E-02 | 0.419 | 0.828 | 3 |
NFKBIA | P25963 | NFKB inhibitor alpha | 0.99 | 0.509 | 0.724 | 3 | |
TNFSF13B | Q9Y275 | TNF superfamily member 13b | 0.98 | 0.526 | 0.724 | 3 | |
CCR7 | P32248 | C-C motif chemokine receptor 7 | 5.3E-02 | 0.477 | 0.759 | 2 | |
ID3 | Q02535 | inhibitor of DNA binding 3, HLH protein | transcription factor | 0.73 | 0.621 | 0.655 | 2 |
RORC | P51449 | RAR related orphan receptor C | 1.00 | 0.609 | 0.655 | 2 | |
ST14 | Q9Y5Y6 | suppression of tumorigenicity 14 | hydrolase; protease | 0.57 | 0.550 | 0.724 | 2 |
TGFB1 | P01137 | transforming growth factor beta 1 | signaling molecule | 0.17 | 0.336 | 0.931 | 2 |
THBS1 | P07996 | thrombospondin 1 | 1.00 | 0.448 | 0.759 | 2 |