Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 2724 31
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 1679 21
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962 1558 50
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885 1206 36
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962 996 23
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885 985 137
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885 933 59
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846 854 163
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923 765 43
CTLA4 P16410 cytotoxic T-lymphocyte associated protein 4 0.94 0.369 0.923 722 24
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846 654 55
CXCL10 P02778 C-X-C motif chemokine ligand 10 Signaling 0.37 0.378 0.885 631 9
MUC1 P15941 mucin 1, cell surface associated 1.9E-02 0.384 0.885 594 18
CD14 P08571 CD14 molecule 4.9E-05 0.392 0.885 551 8
CCL5 P13501 C-C motif chemokine ligand 5 Signaling 1.8E-03 0.403 0.885 514 6
GPT P24298 glutamic--pyruvic transaminase Enzyme 3.6E-19 0.403 0.923 511 9
CCR5 P51681 C-C motif chemokine receptor 5 (gene/pseudogene) G-protein coupled receptor 4.3E-10 0.398 0.885 508 15
DNMT1 P26358 DNA methyltransferase 1 Epigenetic regulator 1.00 0.406 0.885 496 36
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846 462 173
CCR2 P41597 C-C motif chemokine receptor 2 2.3E-02 0.418 0.846 436 7
TRPV4 Q9HBA0 transient receptor potential cation channel subfamily V member 4 Ion channel 2.2E-16 0.457 0.808 422 56
NOTCH3 Q9UM47 notch receptor 3 0.41 0.435 0.808 418 71
PTPN22 Q9Y2R2 protein tyrosine phosphatase non-receptor type 22 3.5E-21 0.438 0.846 400 21
VHL P40337 von Hippel-Lindau tumor suppressor Enzyme 8.0E-02 0.443 0.846 372 215