Source: ANIMAL_MODELS

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962 94
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923 86
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923 71
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885 62
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846 48
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923 47
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885 45
BAX Q07812 BCL2 associated X, apoptosis regulator Signaling 0.32 0.417 0.885 44
MFN2 O95140 mitofusin 2 Enzyme 0.99 0.471 0.846 38
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962 34
CCR5 P51681 C-C motif chemokine receptor 5 (gene/pseudogene) G-protein coupled receptor 4.3E-10 0.398 0.885 26
CD40LG P29965 CD40 ligand Signaling 0.72 0.414 0.846 26
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962 22
HSPD1 P10809 heat shock protein family D (Hsp60) member 1 0.99 0.432 0.808 20
TXNIP Q9H3M7 thioredoxin interacting protein 0.16 0.490 0.731 17
AKR1B1 P15121 aldo-keto reductase family 1 member B Enzyme 2.0E-05 0.491 0.885 15
OPA1 O60313 OPA1 mitochondrial dynamin like GTPase Enzyme modulator 0.99 0.510 0.846 15
SLC9A1 P19634 solute carrier family 9 member A1 Transporter 0.79 0.550 0.731 15
CD40 P25942 CD40 molecule 0.85 0.396 0.846 14
PRKCD Q05655 protein kinase C delta Kinase 1.00 0.480 0.846 14
KCNJ11 Q14654 potassium inwardly rectifying channel subfamily J member 11 Ion channel 1.1E-02 0.529 0.615 12
GHSR Q92847 growth hormone secretagogue receptor G-protein coupled receptor 6.6E-03 0.528 0.769 11
PENK P01210 proenkephalin Signaling 2.1E-04 0.560 0.808 11
RAMP2 O60895 receptor activity modifying protein 2 Receptor 5.1E-02 0.626 0.654 11