Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923 1213 54
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846 854 163
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885 816 119
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769 816 64
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885 698 29
NOTCH1 P46531 notch receptor 1 1.00 0.369 0.885 693 64
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808 611 17
F5 P12259 coagulation factor V Enzyme 5.9E-15 0.441 0.846 369 52
LPA P08519 lipoprotein(a) Enzyme 6.6E-89 0.444 0.769 340 49
IFIH1 Q9BYX4 interferon induced with helicase C domain 1 7.0E-44 0.471 0.808 319 25
COL4A1 P02462 collagen type IV alpha 1 chain 1.00 0.484 0.731 277 62
OFD1 O75665 OFD1 centriole and centriolar satellite protein 0.96 0.510 0.808 261 125
ADAR P55265 adenosine deaminase RNA specific Enzyme 2.6E-02 0.501 0.808 256 32
TREX1 Q9NSU2 three prime repair exonuclease 1 0.58 0.517 0.808 241 36
DLL4 Q9NR61 delta like canonical Notch ligand 4 1.00 0.494 0.769 219 15
GPX4 P36969 glutathione peroxidase 4 Enzyme 4.8E-05 0.516 0.808 201 9
KIF1A Q12756 kinesin family member 1A Cellular structure 1.00 0.559 0.692 187 45
SAMHD1 Q9Y3Z3 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 6.5E-13 0.547 0.769 169 26
RBPJ Q06330 recombination signal binding protein for immunoglobulin kappa J region Nucleic acid binding 1.00 0.518 0.808 161 13
TCTN3 Q6NUS6 tectonic family member 3 4.2E-12 0.566 0.615 136 6
COL4A2 P08572 collagen type IV alpha 2 chain 3.6E-15 0.563 0.654 131 38
RNASEH2C Q8TDP1 ribonuclease H2 subunit C 5.5E-03 0.590 0.731 120 11
RNASEH2A O75792 ribonuclease H2 subunit A Enzyme 4.2E-03 0.592 0.692 116 18
RNASEH2B Q5TBB1 ribonuclease H2 subunit B 3.3E-09 0.595 0.615 115 24