Source: GENOMICS_ENGLAND

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808 18
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846 17
EIF4A3 P38919 eukaryotic translation initiation factor 4A3 1.00 0.608 0.500 12
GDF6 Q6KF10 growth differentiation factor 6 0.99 0.587 0.500 8
CHD7 Q9P2D1 chromodomain helicase DNA binding protein 7 1.00 0.441 0.846 7
FREM2 Q5SZK8 FRAS1 related extracellular matrix 2 3.6E-11 0.566 0.577 7
SALL1 Q9NSC2 spalt like transcription factor 1 Transcription factor 1.00 0.539 0.808 7
TFAP2A P05549 transcription factor AP-2 alpha Transcription factor 0.99 0.488 0.769 7
EDNRA P25101 endothelin receptor type A G-protein coupled receptor 0.99 0.426 0.885 6
EVC P57679 EvC ciliary complex subunit 1 3.5E-25 0.587 0.577 6
EYA1 Q99502 EYA transcriptional coactivator and phosphatase 1 0.95 0.531 0.731 6
GNAI3 P08754 G protein subunit alpha i3 Enzyme modulator 3.8E-02 0.653 0.615 6
GRIP1 Q9Y3R0 glutamate receptor interacting protein 1 0.51 0.581 0.769 6
OTX2 P32243 orthodenticle homeobox 2 Transcription factor 0.92 0.514 0.808 6
FGF10 O15520 fibroblast growth factor 10 Signaling 0.94 0.530 0.692 5
FRAS1 Q86XX4 Fraser extracellular matrix complex subunit 1 3.1E-45 0.560 0.577 5
PLCB4 Q15147 phospholipase C beta 4 Enzyme 3.0E-06 0.610 0.731 5
SIX1 Q15475 SIX homeobox 1 Transcription factor 0.65 0.496 0.692 5
CDC6 Q99741 cell division cycle 6 1.1E-09 0.552 0.731 4
CDT1 Q9H211 chromatin licensing and DNA replication factor 1 2.6E-10 0.597 0.731 4
LEMD3 Q9Y2U8 LEM domain containing 3 1.00 0.582 0.731 4
ORC1 Q13415 origin recognition complex subunit 1 Nucleic acid binding 1.7E-14 0.595 0.654 4
ORC4 O43929 origin recognition complex subunit 4 Nucleic acid binding 7.6E-13 0.612 0.654 4
ORC6 Q9Y5N6 origin recognition complex subunit 6 Nucleic acid binding 3.4E-07 0.628 0.577 4