Source: BEFREE

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 2475 28
IL6 P05231 interleukin 6 0.32 0.248 0.962 2132 21
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 1533 21
IFNG P01579 interferon gamma 0.47 0.288 0.962 1361 10
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885 1214 67
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962 1173 9
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885 1156 29
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962 1030 52
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962 994 8
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923 990 7
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923 953 13
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962 951 4
IL2 P60568 interleukin 2 0.48 0.336 0.885 894 4
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885 765 17
TLR2 O60603 toll like receptor 2 1.0E-06 0.361 0.923 704 15
CD44 P16070 CD44 molecule (Indian blood group) 2.4E-07 0.363 0.962 664 32
IFNA1 P01562 interferon alpha 1 0.371 0.923 646 6
IFNA13 P01562 interferon alpha 13 0.374 0.923 646 4
FOXP3 Q9BZS1 forkhead box P3 0.99 0.368 0.846 622 12
CTLA4 P16410 cytotoxic T-lymphocyte associated protein 4 0.94 0.369 0.923 600 18
CXCL10 P02778 C-X-C motif chemokine ligand 10 Signaling 0.37 0.378 0.885 593 8
HLA-A P04439 major histocompatibility complex, class I, A 1.3E-03 0.370 0.846 583 19
KRT20 P35900 keratin 20 9.1E-11 0.388 0.846 545 1
EZH2 Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 1.00 0.376 0.885 535 18