Source: INFERRED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923 283
ELN P15502 elastin 2.1E-14 0.415 0.885 257
HLA-B P01889 major histocompatibility complex, class I, B 3.9E-05 0.379 0.885 239
ERCC2 P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 7.1E-20 0.420 0.846 220
BAZ1B Q9UIG0 bromodomain adjacent to zinc finger domain 1B 1.00 0.530 0.731 202
DHCR7 Q9UBM7 7-dehydrocholesterol reductase Enzyme 3.9E-13 0.500 0.846 193
PIEZO2 Q9H5I5 piezo type mechanosensitive ion channel component 2 Ion channel 8.1E-07 0.529 0.769 187
TBL2 Q9Y4P3 transducin beta like 2 1.8E-04 0.538 0.731 185
JMJD1C Q15652 jumonji domain containing 1C 1.00 0.517 0.769 169
FAS P25445 Fas cell surface death receptor 0.81 0.372 0.923 168
TGFBR2 P37173 transforming growth factor beta receptor 2 Kinase 0.13 0.413 0.846 159
COL11A1 P12107 collagen type XI alpha 1 chain 1.00 0.495 0.846 158
PLA2G6 O60733 phospholipase A2 group VI Enzyme modulator 2.5E-10 0.476 0.846 145
NOTCH3 Q9UM47 notch receptor 3 0.41 0.435 0.808 142
SMAD3 P84022 SMAD family member 3 Transcription factor 0.80 0.415 0.923 137
KCNQ1 P51787 potassium voltage-gated channel subfamily Q member 1 Ion channel 4.5E-08 0.485 0.769 131
COL4A1 P02462 collagen type IV alpha 1 chain 1.00 0.484 0.731 130
GATA4 P43694 GATA binding protein 4 0.49 0.458 0.846 130
INSR P06213 insulin receptor Kinase 3.6E-05 0.432 0.846 128
VPS13B Q7Z7G8 vacuolar protein sorting 13 homolog B 2.5E-45 0.579 0.769 127
ADAR P55265 adenosine deaminase RNA specific Enzyme 2.6E-02 0.501 0.808 122
ARID1A O14497 AT-rich interaction domain 1A 1.00 0.455 0.846 121
NF1 P21359 neurofibromin 1 Enzyme modulator 0.90 0.440 0.885 119
ALMS1 Q8TCU4 ALMS1 centrosome and basal body associated protein 4.5E-60 0.559 0.808 118