Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885 1456 27
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962 1049 62
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923 992 56
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923 859 12
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885 816 119
FN1 P02751 fibronectin 1 Signaling 1.4E-03 0.365 0.962 724 33
HMGB1 P09429 high mobility group box 1 Nucleic acid binding 0.82 0.368 0.923 724 10
CD34 P28906 CD34 molecule 5.0E-06 0.368 0.808 674 3
FGF2 P09038 fibroblast growth factor 2 Signaling 1.8E-02 0.383 0.923 635 7
IGF1R P08069 insulin like growth factor 1 receptor Kinase 0.97 0.399 0.885 556 92
HSPA4 P34932 heat shock protein family A (Hsp70) member 4 1.00 0.394 0.923 550 7
CYP19A1 P11511 cytochrome P450 family 19 subfamily A member 1 Enzyme 1.7E-05 0.410 0.885 519 77
CFTR P13569 CF transmembrane conductance regulator Ion channel 2.2E-58 0.424 0.885 476 673
SMAD3 P84022 SMAD family member 3 Transcription factor 0.80 0.415 0.923 470 95
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923 469 292
WNK1 Q9H4A3 WNK lysine deficient protein kinase 1 Kinase 1.00 0.416 0.846 460 26
INSR P06213 insulin receptor Kinase 3.6E-05 0.432 0.846 452 109
DPP4 P27487 dipeptidyl peptidase 4 Enzyme 7.3E-09 0.420 0.808 451 13
WT1 P19544 WT1 transcription factor Nucleic acid binding 1.00 0.422 0.808 446 61
NCAM1 P13591 neural cell adhesion molecule 1 1.00 0.415 0.885 445 34
MGMT P16455 O-6-methylguanine-DNA methyltransferase 1.2E-07 0.412 0.885 444 24
HLA-C P10321 major histocompatibility complex, class I, C 1.6E-06 0.415 0.846 435 56
BMP2 P12643 bone morphogenetic protein 2 Signaling 0.99 0.432 0.846 428 12
RUNX1 Q01196 RUNX family transcription factor 1 Transcription factor 0.65 0.425 0.808 412 75