Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
IL6 P05231 interleukin 6 0.32 0.248 0.962 2367 22
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885 1456 27
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962 1250 33
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846 1228 107
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962 1157 8
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923 1011 8
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885 960 48
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885 816 119
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923 783 28
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808 715 92
CD44 P16070 CD44 molecule (Indian blood group) 2.4E-07 0.363 0.962 711 47
CD34 P28906 CD34 molecule 5.0E-06 0.368 0.808 674 3
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923 666 9
IFNA1 P01562 interferon alpha 1 0.371 0.923 662 6
EPO P01588 erythropoietin 1.1E-02 0.381 0.885 646 11
IFNA13 P01562 interferon alpha 13 0.374 0.923 646 4
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885 644 54
NGF P01138 nerve growth factor Signaling 0.82 0.391 0.885 616 11
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808 611 17
IL13 P35225 interleukin 13 1.4E-02 0.386 0.846 587 9
IL2RA P01589 interleukin 2 receptor subunit alpha Receptor 5.5E-02 0.389 0.885 540 43
NOS1 P29475 nitric oxide synthase 1 1.00 0.408 0.885 521 38
PDGFRB P09619 platelet derived growth factor receptor beta Kinase 0.90 0.416 0.846 492 30
CALR P27797 calreticulin Calcium-binding protein 0.89 0.413 0.923 487 9