Source: INFERRED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923 382
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808 381
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846 342
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885 330
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846 327
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846 307
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923 286
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923 283
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769 266
ELN P15502 elastin 2.1E-14 0.415 0.885 257
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885 224
GLI3 P10071 GLI family zinc finger 3 1.00 0.436 0.846 218
MED12 Q93074 mediator complex subunit 12 Transcription factor 1.00 0.476 0.769 216
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808 216
PEX6 Q13608 peroxisomal biogenesis factor 6 6.3E-06 0.547 0.731 212
PEX1 O43933 peroxisomal biogenesis factor 1 1.1E-14 0.538 0.769 209
TBX1 O43435 T-box transcription factor 1 Transcription factor 0.84 0.433 0.808 207
KMT2A Q03164 lysine methyltransferase 2A 1.00 0.410 0.885 205
BAZ1B Q9UIG0 bromodomain adjacent to zinc finger domain 1B 1.00 0.530 0.731 202
DHCR7 Q9UBM7 7-dehydrocholesterol reductase Enzyme 3.9E-13 0.500 0.846 193
TRPV4 Q9HBA0 transient receptor potential cation channel subfamily V member 4 Ion channel 2.2E-16 0.457 0.808 192
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962 187
ARX Q96QS3 aristaless related homeobox 0.91 0.516 0.654 187
GTF2I P78347 general transcription factor IIi 1.00 0.500 0.808 187