Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885 1368 68
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923 1193 57
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885 644 54
CALR P27797 calreticulin Calcium-binding protein 0.89 0.413 0.923 487 9
CASP8 Q14790 caspase 8 Enzyme 3.7E-06 0.404 0.923 480 32
XRCC1 P18887 X-ray repair cross complementing 1 6.3E-09 0.421 0.923 410 39
ABL1 P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 1.00 0.432 0.923 395 37
BCR P11274 BCR activator of RhoGEF and GTPase Enzyme modulator 0.99 0.431 0.885 392 7
STAT5B P51692 signal transducer and activator of transcription 5B Nucleic acid binding 1.00 0.442 0.808 357 14
STAT5A P42229 signal transducer and activator of transcription 5A Nucleic acid binding 1.00 0.445 0.808 318 6
APEX1 P27695 apurinic/apyrimidinic endodeoxyribonuclease 1 1.9E-07 0.458 0.846 305 14
ASXL1 Q8IXJ9 ASXL transcriptional regulator 1 1.3E-14 0.482 0.808 296 24
CASP9 P55211 caspase 9 Enzyme 7.4E-06 0.458 0.808 293 22
MMRN1 Q13201 multimerin 1 2.1E-25 0.465 0.846 272 3
JAK1 P23458 Janus kinase 1 Kinase 1.00 0.474 0.769 239 41
MPL P40238 MPL proto-oncogene, thrombopoietin receptor Receptor 4.1E-09 0.510 0.692 222 31
RUNX1T1 Q06455 RUNX1 partner transcriptional co-repressor 1 Transcription factor 0.98 0.530 0.808 137 11
MVD P53602 mevalonate diphosphate decarboxylase 2.7E-17 0.568 0.769 101 11
CDR1 P51861 cerebellar degeneration related protein 1 0.576 0.808 87 0
AKR1C4 P17516 aldo-keto reductase family 1 member C4 Enzyme 2.2E-17 0.587 0.846 76 2
PRB1 P04280 proline rich protein BstNI subfamily 1 (gene/pseudogene) 8.4E-11 0.621 0.692 54 4
SNRPF P62306 small nuclear ribonucleoprotein polypeptide F Nucleic acid binding 0.79 0.805 0.154 14 2
HMGXB3 Q12766 HMG-box containing 3 1.00 0.821 0.115 9 1