| Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI g | DPI g | Num. diseases | Num. SNPs |
|---|---|---|---|---|---|---|---|---|
| STK11 | Q15831 | serine/threonine kinase 11 | Kinase | 0.99 | 0.435 | 0.808 | 12 | 18 |
| BRCA2 | P51587 | BRCA2 DNA repair associated | Nucleic acid binding | 2.4E-25 | 0.379 | 0.846 | 8 | 78 |
| KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 | 8 | 18 |
| VHL | P40337 | von Hippel-Lindau tumor suppressor | Enzyme | 8.0E-02 | 0.443 | 0.846 | 5 | 67 |
| PTPRT | O14522 | protein tyrosine phosphatase receptor type T | Enzyme | 1.00 | 0.636 | 0.538 | 4 | 5 |
| PPP2R1B | P30154 | protein phosphatase 2 scaffold subunit Abeta | Enzyme | 3.0E-15 | 0.678 | 0.423 | 3 | 5 |
| BAP1 | Q92560 | BRCA1 associated protein 1 | Enzyme | 0.99 | 0.454 | 0.731 | 1 | 0 |