| Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI g | DPI g | Num. diseases | Num. SNPs |
|---|---|---|---|---|---|---|---|---|
| PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 | 1277 | 41 |
| AKT1 | P31749 | AKT serine/threonine kinase 1 | Kinase | 0.98 | 0.311 | 0.962 | 1011 | 29 |
| MAPT | P10636 | microtubule associated protein tau | 6.0E-03 | 0.446 | 0.923 | 256 | 74 | |
| TSC1 | Q92574 | TSC complex subunit 1 | 1.00 | 0.440 | 0.808 | 248 | 12 | |
| NPR2 | P20594 | natriuretic peptide receptor 2 | Kinase | 4.2E-05 | 0.573 | 0.615 | 64 | 2 |
| GRIN3A | Q8TCU5 | glutamate ionotropic receptor NMDA type subunit 3A | Ion channel | 0.45 | 0.743 | 0.423 | 21 | 2 |