Source: BEFREE

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 2475 28
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962 2245 232
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962 1334 32
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962 1173 9
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923 1034 19
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962 932 19
IL2 P60568 interleukin 2 0.48 0.336 0.885 894 4
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923 839 21
VDR P11473 vitamin D receptor Nuclear receptor 1.7E-05 0.352 0.885 757 66
CXCR4 P61073 C-X-C motif chemokine receptor 4 G-protein coupled receptor 1.8E-02 0.362 0.923 681 20
IL18 Q14116 interleukin 18 3.1E-02 0.365 0.923 673 18
CD44 P16070 CD44 molecule (Indian blood group) 2.4E-07 0.363 0.962 664 32
CD34 P28906 CD34 molecule 5.0E-06 0.368 0.808 663 1
FOXP3 Q9BZS1 forkhead box P3 0.99 0.368 0.846 622 12
CXCL10 P02778 C-X-C motif chemokine ligand 10 Signaling 0.37 0.378 0.885 593 8
HLA-A P04439 major histocompatibility complex, class I, A 1.3E-03 0.370 0.846 583 19
GSTM1 P09488 glutathione S-transferase mu 1 2.1E-03 0.380 0.923 581 8
HPGDS O60760 hematopoietic prostaglandin D synthase 1.8E-06 0.388 0.923 560 4
CSF3 P09919 colony stimulating factor 3 0.38 0.377 0.885 552 2
EZH2 Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 1.00 0.376 0.885 535 18
IL22 Q9GZX6 interleukin 22 1.9E-04 0.393 0.885 532 9
TERT O14746 telomerase reverse transcriptase Enzyme 0.99 0.374 0.846 525 37
GSTT1 P30711 glutathione S-transferase theta 1 1.5E-04 0.393 0.923 497 0
HLA-B P01889 major histocompatibility complex, class I, B 3.9E-05 0.379 0.885 492 40