Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885 960 48
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769 816 64
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808 731 141
KMT2A Q03164 lysine methyltransferase 2A 1.00 0.410 0.885 535 65
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923 528 56
WNT5A P41221 Wnt family member 5A Signaling 0.99 0.443 0.808 375 11
SETBP1 Q9Y6X0 SET binding protein 1 1.00 0.503 0.808 257 28
SMC1A Q14683 structural maintenance of chromosomes 1A 1.00 0.509 0.808 251 53
ROR2 Q01974 receptor tyrosine kinase like orphan receptor 2 Kinase 1.2E-04 0.498 0.731 250 20
HDAC8 Q9BY41 histone deacetylase 8 Epigenetic regulator 0.98 0.511 0.885 236 28
IRF6 O14896 interferon regulatory factor 6 Transcription factor 1.00 0.486 0.769 233 43
NIPBL Q6KC79 NIPBL cohesin loading factor Nucleic acid binding 1.00 0.521 0.808 225 270
FIG4 Q92562 FIG4 phosphoinositide 5-phosphatase 2.3E-34 0.551 0.731 223 32
POR P16435 cytochrome p450 oxidoreductase 3.4E-10 0.502 0.769 218 21
SMC3 Q9UQE7 structural maintenance of chromosomes 3 1.00 0.535 0.846 193 21
RAD21 O60216 RAD21 cohesin complex component 1.00 0.528 0.846 192 19
DVL1 O14640 dishevelled segment polarity protein 1 Signaling 3.7E-06 0.531 0.769 181 16
DVL3 Q92997 dishevelled segment polarity protein 3 Signaling 0.39 0.537 0.731 167 6
SETD5 Q9C0A6 SET domain containing 5 1.00 0.560 0.731 161 22
B3GLCT Q6Y288 beta 3-glucosyltransferase Enzyme 7.1E-17 0.554 0.731 157 11
GMNN O75496 geminin DNA replication inhibitor 0.11 0.554 0.808 153 3
RAB3GAP2 Q9H2M9 RAB3 GTPase activating non-catalytic protein subunit 2 Enzyme modulator 0.99 0.584 0.769 143 9
SLC25A24 Q6NUK1 solute carrier family 25 member 24 Transporter 3.4E-12 0.575 0.731 141 5
VAC14 Q08AM6 VAC14 component of PIKFYVE complex Receptor 0.19 0.588 0.731 140 12