Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962 2494 527
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923 1511 83
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885 1456 27
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885 1394 183
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885 1368 68
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846 1228 107
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923 1044 15
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923 1011 8
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885 933 59
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885 816 119
PROM1 O43490 prominin 1 Transporter 1.9E-22 0.410 0.846 477 33
GFAP P14136 glial fibrillary acidic protein 1.5E-06 0.421 0.885 447 99
ABCG2 Q9UNQ0 ATP binding cassette subfamily G member 2 (Junior blood group) Transporter 2.1E-32 0.419 0.885 420 68
ABCB6 Q9NP58 ATP binding cassette subfamily B member 6 (Langereis blood group) Transporter 8.6E-19 0.431 0.885 400 19
IDH1 O75874 isocitrate dehydrogenase (NADP(+)) 1 2.6E-12 0.424 0.808 399 10
IDH2 P48735 isocitrate dehydrogenase (NADP(+)) 2 0.88 0.434 0.808 380 15
DHDDS Q86SQ9 dehydrodolichyl diphosphate synthase subunit Enzyme 0.25 0.468 0.885 308 15
NES P48681 nestin 1.6E-06 0.450 0.808 302 4
PAX3 P23760 paired box 3 0.24 0.481 0.769 257 62
MBD2 Q9UBB5 methyl-CpG binding domain protein 2 Epigenetic regulator 0.35 0.466 0.846 256 5
CHPT1 Q8WUD6 choline phosphotransferase 1 Enzyme 2.4E-04 0.474 0.846 253 7
MSC O60682 musculin 2.5E-02 0.475 0.846 241 0
MIR20A microRNA 20a 0.498 0.769 180 3
CD276 Q5ZPR3 CD276 molecule Enzyme modulator 2.5E-09 0.505 0.731 169 3