| Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI g | DPI g | Num. diseases | Num. SNPs |
|---|---|---|---|---|---|---|---|---|
| BRAF | P15056 | B-Raf proto-oncogene, serine/threonine kinase | Kinase | 1.00 | 0.319 | 0.846 | 125 | 84 |
| PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 | 85 | 55 |
| TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 | 84 | 390 |
| H3-3A | P84243 | H3.3 histone A | 0.12 | 0.559 | 0.692 | 68 | 3 | |
| FGFR1 | P11362 | fibroblast growth factor receptor 1 | Kinase | 1.00 | 0.362 | 0.885 | 27 | 63 |
| EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 | 23 | 50 |
| IDH1 | O75874 | isocitrate dehydrogenase (NADP(+)) 1 | 2.6E-12 | 0.424 | 0.808 | 18 | 2 | |
| IDH2 | P48735 | isocitrate dehydrogenase (NADP(+)) 2 | 0.88 | 0.434 | 0.808 | 9 | 5 | |
| ACVR1 | Q04771 | activin A receptor type 1 | Kinase | 0.33 | 0.535 | 0.731 | 4 | 10 |
| H3C11 | P68431 | H3 clustered histone 11 | 8.5E-03 | 0.663 | 0.308 | 2 | 2 |