Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962 2494 527
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962 1028 7
CD34 P28906 CD34 molecule 5.0E-06 0.368 0.808 674 3
EPO P01588 erythropoietin 1.1E-02 0.381 0.885 646 11
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885 644 54
CD14 P08571 CD14 molecule 4.9E-05 0.392 0.885 551 8
HSPA4 P34932 heat shock protein family A (Hsp70) member 4 1.00 0.394 0.923 550 7
HTC2 hypertrichosis 2 (generalized, congenital) 0.392 0.808 511 0
MIR146A microRNA 146a 0.398 0.885 505 3
MYD88 Q99836 MYD88 innate immune signal transduction adaptor Enzyme modulator 0.12 0.414 0.923 480 9
EGR1 P18146 early growth response 1 Nucleic acid binding 0.35 0.433 0.923 378 3
S100A8 P05109 S100 calcium binding protein A8 Calcium-binding protein 0.14 0.430 0.962 369 2
TTN Q8WZ42 titin Kinase 2.6E-96 0.470 0.885 366 651
MIR145 microRNA 145 0.431 0.846 366 4
IL5 P05113 interleukin 5 5.7E-03 0.437 0.846 359 9
CSF1R P07333 colony stimulating factor 1 receptor Kinase 0.13 0.448 0.808 356 60
F2R P25116 coagulation factor II thrombin receptor G-protein coupled receptor 8.5E-03 0.444 0.846 347 10
SPARC P09486 secreted protein acidic and cysteine rich Signaling 0.89 0.445 0.846 344 13
CCR7 P32248 C-C motif chemokine receptor 7 G-protein coupled receptor 5.8E-02 0.443 0.769 320 3
FLI1 Q01543 Fli-1 proto-oncogene, ETS transcription factor Transcription factor 0.99 0.468 0.692 318 17
ANXA5 P08758 annexin A5 3.8E-15 0.458 0.769 283 10
NPM1 P06748 nucleophosmin 1 Chaperone 1.00 0.464 0.846 283 7
IRF1 P10914 interferon regulatory factor 1 Transcription factor 0.99 0.468 0.769 257 7
KITLG P21583 KIT ligand 0.85 0.473 0.885 249 23