Source: BEFREE

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
MAPK3 P27361 mitogen-activated protein kinase 3 Kinase 3.7E-02 0.379 0.885 577 7
THBS1 P07996 thrombospondin 1 1.00 0.407 0.885 448 10
AHR P35869 aryl hydrocarbon receptor Transcription factor 1.00 0.410 0.923 428 11
TRPV1 Q8NER1 transient receptor potential cation channel subfamily V member 1 Ion channel 1.0E-16 0.446 0.885 381 6
JAG1 P78504 jagged canonical Notch ligand 1 1.00 0.429 0.808 322 5
FMR1 Q06787 FMRP translational regulator 1 Nucleic acid binding 0.65 0.473 0.769 241 2
RPS19 P39019 ribosomal protein S19 Nucleic acid binding 0.92 0.480 0.846 200 3
SPZ1 Q9BXG8 spermatogenic leucine zipper 1 0.507 0.769 171 0
CRISP2 P16562 cysteine rich secretory protein 2 Immune response 1.4E-12 0.512 0.769 167 1
PRSS55 Q6UWB4 serine protease 55 Enzyme 3.2E-11 0.513 0.769 163 0
SCLY Q96I15 selenocysteine lyase Enzyme 2.3E-09 0.530 0.731 159 0
PC P11498 pyruvate carboxylase Enzyme 1.4E-02 0.515 0.808 149 4
THBS2 P35442 thrombospondin 2 0.56 0.526 0.769 138 9
GAD2 Q05329 glutamate decarboxylase 2 Enzyme 0.75 0.529 0.731 135 7
HTR2C P28335 5-hydroxytryptamine receptor 2C G-protein coupled receptor 3.7E-02 0.555 0.692 122 11
KCNMA1 Q12791 potassium calcium-activated channel subfamily M alpha 1 Ion channel 1.00 0.518 0.846 119 10
SELENOP P49908 selenoprotein P Extracellular structure 8.3E-07 0.545 0.769 108 5
LOH19CR1 loss of heterozygosity, 19, chromosomal region 1 0.569 0.808 96 0
EGR2 P11161 early growth response 2 Nucleic acid binding 0.50 0.547 0.769 84 13
DBA2 Diamond-Blackfan anemia 2 0.599 0.731 74 0
EGR3 Q06889 early growth response 3 Nucleic acid binding 0.95 0.599 0.731 69 2
SYN1 P17600 synapsin I Cellular structure 0.99 0.597 0.462 66 11
ADGRV1 Q8WXG9 adhesion G protein-coupled receptor V1 G-protein coupled receptor 3.2E-39 0.572 0.731 48 2
BACE2 Q9Y5Z0 beta-secretase 2 Enzyme 6.8E-03 0.628 0.615 47 1