Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923 1059 13
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923 1021 43
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885 985 137
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885 816 119
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769 816 64
EPHB2 P29323 EPH receptor B2 Kinase 1.00 0.374 0.846 649 19
IGF2 P01344 insulin like growth factor 2 4.4E-02 0.390 0.885 604 19
FLNA P21333 filamin A 1.00 0.419 0.846 571 85
CHD7 Q9P2D1 chromodomain helicase DNA binding protein 7 1.00 0.441 0.846 419 247
COL11A2 P13942 collagen type XI alpha 2 chain 0.70 0.435 0.846 399 37
GJB2 P29033 gap junction protein beta 2 Cell-cell junction 6.6E-16 0.441 0.846 392 132
AFP P02771 alpha fetoprotein Transporter 1.1E-11 0.429 0.885 392 9
FLNB O75369 filamin B 6.1E-10 0.458 0.923 374 51
MMP14 P50281 matrix metallopeptidase 14 Enzyme 1.00 0.447 0.769 340 7
GPC3 P51654 glypican 3 1.00 0.466 0.808 311 16
LBR Q14739 lamin B receptor Enzyme 0.18 0.473 0.808 307 17
CDKN1C P49918 cyclin dependent kinase inhibitor 1C 0.82 0.456 0.846 298 32
KCNQ1 P51787 potassium voltage-gated channel subfamily Q member 1 Ion channel 4.5E-08 0.485 0.769 281 380
COL11A1 P12107 collagen type XI alpha 1 chain 1.00 0.495 0.846 268 41
HOXD13 P35453 homeobox D13 8.6E-03 0.483 0.808 259 19
LRP2 P98164 LDL receptor related protein 2 1.00 0.491 0.846 254 51
LRP1 Q07954 LDL receptor related protein 1 1.00 0.482 0.769 252 23
PITX2 Q99697 paired like homeodomain 2 0.98 0.489 0.808 248 27
H19 H19 imprinted maternally expressed transcript 0.494 0.923 242 15